Adenylosuccinate lyase (ADSL) Recombinant Protein | ADSL recombinant protein
Recombinant Chicken Adenylosuccinate lyase (ADSL)
Gene Names
ADSL; purB
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Adenylosuccinate lyase (ADSL); Recombinant Chicken Adenylosuccinate lyase (ADSL); ADSL recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-485, Full length protein
Sequence
MATPCAEEDPLARYRSPLVSRYASAEMGFNFSERKKFGTWRRLWLYLAQAEKSLGLPITDEQIKEMEANLDNIDFKMAAEEEKKLRHDVMAHVHTFAHCCPKAAAIIHLGATSCYVGDNTDLIVLRDGFNLLLPKLARVISRLADFAETHADLPTLGFTHYQPAQLTTVGKRCCLWIQDLCMDLQNLERARDDLRFRGVKGTTGTQASFLQLFEGDHSKVEELDRLVTAKAGFKRSYMVTGQTYSRKVDIEVLSVLASLGASVHKICTDIRLLANLKEIEEPFEKDQIGSSAMPYKRNPMRSERCCSLARHLMTLVLDPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIDRRIRQELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQQAAAVVKQEGGDNDFIARVRADPYFSPIHEHLDSLLDPSSFTGRAPQQVAKFLKEEVRPALIPYQSMMGGKIELTL
Sequence Length
485
Species
Chicken
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for ADSL recombinant protein
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,653 Da
NCBI Official Full Name
adenylosuccinate lyase
NCBI Official Synonym Full Names
adenylosuccinate lyase
NCBI Official Symbol
ADSL
NCBI Official Synonym Symbols
purB
NCBI Protein Information
adenylosuccinate lyase
UniProt Protein Name
Adenylosuccinate lyase
Protein Family
UniProt Gene Name
ADSL
UniProt Synonym Gene Names
ADSL; ASL; ASase
Uniprot Description
Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
Research Articles on ADSL
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Product Notes
The ADSL adsl (Catalog #AAA963325) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-485, Full length protein. The amino acid sequence is listed below: MATPCAEEDP LARYRSPLVS RYASAEMGFN FSERKKFGTW RRLWLYLAQA EKSLGLPITD EQIKEMEANL DNIDFKMAAE EEKKLRHDVM AHVHTFAHCC PKAAAIIHLG ATSCYVGDNT DLIVLRDGFN LLLPKLARVI SRLADFAETH ADLPTLGFTH YQPAQLTTVG KRCCLWIQDL CMDLQNLERA RDDLRFRGVK GTTGTQASFL QLFEGDHSKV EELDRLVTAK AGFKRSYMVT GQTYSRKVDI EVLSVLASLG ASVHKICTDI RLLANLKEIE EPFEKDQIGS SAMPYKRNPM RSERCCSLAR HLMTLVLDPL QTASVQWFER TLDDSANRRV CLAEAFLTAD IILSTLQNIS EGLVVYPKVI DRRIRQELPF MATENIIMAM VKAGGNRQDC HEKIRVLSQQ AAAVVKQEGG DNDFIARVRA DPYFSPIHEH LDSLLDPSSF TGRAPQQVAK FLKEEVRPAL IPYQSMMGGK IELTL. It is sometimes possible for the material contained within the vial of "Adenylosuccinate lyase (ADSL), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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