Activin receptor type-1 (ACVR1) Recombinant Protein | ACVR1 recombinant protein
Recombinant Chicken Activin receptor type-1 (ACVR1), partial
Gene Names
ACVR1; ALK2; ATVR1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Activin receptor type-1 (ACVR1); Recombinant Chicken Activin receptor type-1 (ACVR1); partial; ACVR1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
17-119
Sequence
VQDE ELKLNECVCE GMSCGNGDRC QGQQCFASLS INDGAKVYQK GCFQVYEQGK MTCKTPPSPD QAVECCQGYL CNMNITAKLP SSKGQTLQGE AAGYSMETL
Sequence Length
103
Species
Chicken
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for ACVR1 recombinant protein
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine
threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,225 Da
NCBI Official Full Name
activin receptor type-1
NCBI Official Synonym Full Names
activin A receptor type 1
NCBI Official Symbol
ACVR1
NCBI Official Synonym Symbols
ALK2; ATVR1
NCBI Protein Information
activin receptor type-1
UniProt Protein Name
Activin receptor type-1
Protein Family
UniProt Gene Name
ACVR1
Uniprot Description
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin ().
Research Articles on ACVR1
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Product Notes
The ACVR1 acvr1 (Catalog #AAA1407651) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 17-119. The amino acid sequence is listed below: VQDE ELKLNECVCE GMSCGNGDRC QGQQCFASLS INDGAKVYQK GCFQVYEQGK MTCKTPPSPD QAVECCQGYL CNMNITAKLP SSKGQTLQGE AAGYSMETL. It is sometimes possible for the material contained within the vial of "Activin receptor type-1 (ACVR1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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