Canine Ras-Related Protein Rab-1B (RAB1B) ELISA Kit | RAB1B elisa kit

Canine Ras-Related Protein Rab-1B (RAB1B) ELISA Kit

Cat. Num. AAA9912313

• Reactivity: Canine
• Synonyms: Ras-Related Protein Rab-1B (RAB1B); Canine Ras-Related Protein Rab-1B (RAB1B) ELISA Kit; RAB1B elisa kit

• Reactivity: Canine

• Assay Type: Quantitative Sandwich
• Detection Range: 0.25ng/ml-8ng/ml
• Sensitivity: 0.1ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for RAB1B elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of RAB1B (hereafter termed "analyte") in undiluted original Canine serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 13569962
• NCBI GeneID: 81876
• NCBI Accession #: NP_112243.1
• NCBI GenBank Nucleotide #: NM_030981.3
• UniProt Accession #: Q9H0U4; A8K7S1
• Molecular Weight: 22,171 Da
• NCBI Official Full Name: ras-related protein Rab-1B
• NCBI Official Synonym Full Names: RAB1B, member RAS oncogene family
• NCBI Official Symbol: RAB1B
• NCBI Protein Information: ras-related protein Rab-1B
• UniProt Protein Name: Ras-related protein Rab-1B
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB1B

NCBI Description

Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]

Uniprot Description

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.