Human ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 ELISA Kit | ATP6V0D1 elisa kit

Human V-type proton ATPase subunit d 1, ATP6V0D1 ELISA Kit

Cat. Num. AAA9342971

• Gene Names: ATP6V0D1; P39; VATX; VMA6; ATP6D; ATP6DV; VPATPD
• Reactivity: Human
• Synonyms: ATPase; H+ transporting; lysosomal 38kDa; V0 subunit d1; Human V-type proton ATPase subunit d 1; ATP6V0D1 ELISA Kit; Human V-type proton ATPase subunit d 1 (ATP6V0D1) ELISA kit; ATP6D; ATP6DV; P39; VATX; VMA6; VPATPD; lysosomal (vacuolar proton pump); member D; lysosomal; H (+) -transporting two-sector ATPase; sub; ATP6V0D1 elisa kit

• Reactivity: Human

• Samples: Serum, Plasma and Tissue Homogenate
• Assay Type: Sandwich
• Detection Range: 0.625ng/ml-20ng/ml.
• Sensitivity: 0.1ng/ml.
• Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic applications! This kit is intended to be used for determination the level of ATP6V0D1 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for ATP6V0D1 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of ATP6V0D1 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.

NCBI and Uniprot Product Information

• NCBI GI #: 19913432
• NCBI GeneID: 9114
• NCBI Accession #: NP_004682.2
• NCBI GenBank Nucleotide #: NM_004691.4
• UniProt Accession #: P61421; P12953; Q02547
• Molecular Weight: 40,329 Da
• NCBI Official Full Name: V-type proton ATPase subunit d 1
• NCBI Official Synonym Full Names: ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
• NCBI Official Symbol: ATP6V0D1
• NCBI Official Synonym Symbols: P39; VATX; VMA6; ATP6D; ATP6DV; VPATPD
• NCBI Protein Information: V-type proton ATPase subunit d 1; V-ATPase, subunit D; V-ATPase subunit d 1; V-ATPase AC39 subunit; 32 kDa accessory protein; vacuolar proton pump subunit d 1; V-ATPase 40 KDa accessory protein; H(+)-transporting two-sector ATPase, subunit D; ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D
• UniProt Protein Name: V-type proton ATPase subunit d 1
• Protein Family: V-type proton ATPase
• UniProt Gene Name: ATP6V0D1
• UniProt Synonym Gene Names: ATP6D; VPATPD; V-ATPase subunit d 1; p39
• UniProt Entry Name: VA0D1_HUMAN

NCBI Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008]

Uniprot Description

ATP6V0D1: Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. Belongs to the V-ATPase V0D/AC39 subunit family.

Protein type: Vesicle; EC 3.6.3.14; Hydrolase; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: centrosome; phagocytic vesicle membrane; synaptic vesicle; membrane; lysosomal membrane; early endosome; apical plasma membrane; endosome membrane; nerve terminal; vacuolar proton-transporting V-type ATPase complex

Molecular Function: hydrogen-exporting ATPase activity, phosphorylative mechanism; protein binding; protein complex binding

Biological Process: interaction with host; proton transport; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; cellular iron ion homeostasis; unfolded protein response; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; cilium biogenesis; transferrin transport; brain development; transmembrane transport