Human SET domain, bifurcated 2 ELISA Kit | SETDB2 elisa kit
Human Histone-lysine N-methyltransferase SETDB2, SETDB2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SETDB2: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis. Belongs to the histone-lysine methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Methyltransferase, protein lysine; EC 2.1.1.43; Methyltransferase; Amino Acid Metabolism - lysine degradation
Cellular Component: chromosome; nucleus
Molecular Function: transferase activity; methyltransferase activity; DNA binding; zinc ion binding; metal ion binding; histone lysine N-methyltransferase activity (H3-K9 specific); histone-lysine N-methyltransferase activity
Biological Process: methylation; mitosis; cell division; multicellular organismal development; chromatin modification; cell cycle; chromosome segregation; histone H3-K9 methylation; peptidyl-lysine methylation
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Product Notes
The Human SETDB2 setdb2 (Catalog #AAA9333054) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9333054 ELISA Kit recognizes Human SETDB2. It is sometimes possible for the material contained within the vial of "SET domain, bifurcated 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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