Human G protein-coupled receptor 3 ELISA Kit | GPR3 elisa kit
Human G-protein coupled receptor 3, GPR3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease. [provided by RefSeq, Oct 2012]
Uniprot Description
GPR3: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress, amyloid-beta peptide generation in neurons and neurite outgrowth. Maintains also meiotic arrest in oocytes. Belongs to the G-protein coupled receptor 1 family.
Protein type: Cell cycle regulation; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36.1-p35
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity; protein binding
Biological Process: elevation of cytosolic calcium ion concentration; regulation of meiosis; positive regulation of cAMP metabolic process; G-protein signaling, adenylate cyclase activating pathway
Research Articles on GPR3
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Product Notes
The Human GPR3 gpr3 (Catalog #AAA9317505) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317505 ELISA Kit recognizes Human GPR3. It is sometimes possible for the material contained within the vial of "G protein-coupled receptor 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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