Mouse soc-2 suppressor of clear homolog (C. elegans) ELISA Kit | SHOC2 elisa kit
Mouse Leucine-rich repeat protein SHOC-2, SHOC2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SHOC2: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. Defects in SHOC2 are the cause of Noonan syndrome-like disorder with loose anagen hair (NSLH). A syndrome characterized by Noonan dysmorphic features such as macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck, pectus anomalies, in association with pluckable, sparse, thin and slow-growing hair. Belongs to the SHOC2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Cellular Component: nucleoplasm; cytoplasm; protein phosphatase type 1 complex; nucleus
Molecular Function: protein phosphatase binding
Biological Process: positive regulation of Ras protein signal transduction
Research Articles on SHOC2
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Product Notes
The Mouse SHOC2 shoc2 (Catalog #AAA9317487) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317487 ELISA Kit recognizes Mouse SHOC2. It is sometimes possible for the material contained within the vial of "soc-2 suppressor of clear homolog (C. elegans), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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