Human Hemoglobin Gamma 1 (HBg1) ELISA Kit | HBg1 elisa kit

Human Hemoglobin Gamma 1 (HBg1) ELISA Kit

Cat. Num. AAA9309650

• Gene Names: HBG1; HBGA; HBGR; HSGGL1; PRO2979
• Reactivity: Human
• Synonyms: Hemoglobin Gamma 1 (HBg1); Human Hemoglobin Gamma 1 (HBg1) ELISA Kit; HBg1 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Serum, Plasma and Tissue Homogenate
• Assay Type: Sandwich
• Detection Range: 0.625 ug/ml - 20 ug/ml.
• Sensitivity: 0.1 ug/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for HBg1 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of HBgamma1 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.

NCBI and Uniprot Product Information

• NCBI GI #: 28302131
• NCBI GeneID: 3047
• NCBI Accession #: NP_000550.2
• NCBI GenBank Nucleotide #: NM_000559.2
• UniProt Accession #: P69891; P02096; P62027; Q549G1; Q8TDA1; Q96FH7
• Molecular Weight: 16,140 Da
• NCBI Official Full Name: hemoglobin subunit gamma-1
• NCBI Official Synonym Full Names: hemoglobin, gamma A
• NCBI Official Symbol: HBG1
• NCBI Official Synonym Symbols: HBGA; HBGR; HSGGL1; PRO2979
• NCBI Protein Information: hemoglobin subunit gamma-1; hb F Agamma; gamma globin; A-gamma globin; gamma-1-globin; gamma A hemoglobin; hemoglobin gamma-1 chain; hemoglobin gamma-a chain; hemoglobin, gamma, regulator of
• UniProt Protein Name: Hemoglobin subunit gamma-1
• Protein Family: Hemoglobin
• UniProt Gene Name: HBG1
• UniProt Entry Name: HBG1_HUMAN

NCBI Description

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]

Uniprot Description

HBG1: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: hemoglobin complex; cytosol

Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: oxygen transport; blood coagulation

Disease: Fetal Hemoglobin Quantitative Trait Locus 1