MSRB2 blocking peptide
MSRB2 Antibody (Center) Blocking Peptide
Gene Names
MSRB2; CBS1; MSRB; PILB; CBS-1; CGI-131
Synonyms
MSRB2; MSRB2 Antibody (Center) Blocking Peptide; Methionine-R-sulfoxide reductase B2; mitochondrial; MsrB2; 184-; CBS-1; MSRB; MSRB2 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human MSRB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
182
Cellular Location
Mitochondrion.
Tissue Location
Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for MSRB2 blocking peptide
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post- translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
19,536 Da
NCBI Official Full Name
Methionine-R-sulfoxide reductase B2, mitochondrial
NCBI Official Synonym Full Names
methionine sulfoxide reductase B2
NCBI Official Symbol
MSRB2
NCBI Official Synonym Symbols
CBS1; MSRB; PILB; CBS-1; CGI-131
NCBI Protein Information
methionine-R-sulfoxide reductase B2, mitochondrial
UniProt Protein Name
Methionine-R-sulfoxide reductase B2, mitochondrial
Protein Family
UniProt Gene Name
MSRB2
UniProt Synonym Gene Names
CBS-1; MSRB; MsrB2
UniProt Entry Name
MSRB2_HUMAN
Uniprot Description
MSRB2: Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. Belongs to the MsrB Met sulfoxide reductase family.
Protein type: Transcription factor; EC 1.8.4.-; Mitochondrial; Oxidoreductase
Chromosomal Location of Human Ortholog: 10p12
Cellular Component: cytosol; mitochondrion
Molecular Function: actin binding; peptide-methionine (R)-S-oxide reductase activity; transcription factor activity; zinc ion binding
Biological Process: actin filament polymerization; protein repair
Research Articles on MSRB2
Similar Products
Product Notes
The MSRB2 msrb2 (Catalog #AAA9226464) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MSRB2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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