Bovine Apoptosis-stimulating of p53 protein 2 (TP53BP2) ELISA Kit | TP53BP2 elisa kit
Bovine Apoptosis-stimulating of p53 protein 2 (TP53BP2) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
53BP2: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. Belongs to the ASPP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor
Cellular Component: perinuclear region of cytoplasm; cytoplasm; nucleus
Molecular Function: identical protein binding; NF-kappaB binding; SH3 domain binding
Biological Process: embryonic development ending in birth or egg hatching; central nervous system development; apoptosis; heart development; response to ionizing radiation; cell cycle
Research Articles on TP53BP2
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Product Notes
The Bovine TP53BP2 tp53bp2 (Catalog #AAA7206992) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7206992 ELISA Kit recognizes Bovine TP53BP2. It is sometimes possible for the material contained within the vial of "Apoptosis-stimulating of p53 protein 2 (TP53BP2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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