anti-Mouse Calsarcin-2 Polyclonal Antibody
Anti - Calsarcin-2 (Myozenin-1)
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Serum
Synonyms
Calsarcin-2; Polyclonal Antibody; Anti - Calsarcin-2 (Myozenin-1); Calsarcin-2 (Myozenin-1); anti-Calsarcin-2 antibody
Host
Host: Rabbit
Source: Mouse
Source: Mouse
Reactivity
Mouse
Clonality
Polyclonal
Specificity
Recognizes mouse Calsarcin-2.
Purity/Purification
Serum
Form/Format
Serum
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, 40% glycerol.
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide, 40% glycerol.
Applicable Applications for anti-Calsarcin-2 antibody
ELISA, Western Blot
Application Notes
Suitable for use in ELISA and Western Blot. Other applications not tested.
Dilution: Western Blot: 1:1000-1:5000 (ECL)
ELISA: 1:10,000-1:50,000; Control peptide can be used to coat ELISA plates at 1ug/ml.
Optimal dilutions to be determined by the researcher.
Dilution: Western Blot: 1:1000-1:5000 (ECL)
ELISA: 1:10,000-1:50,000; Control peptide can be used to coat ELISA plates at 1ug/ml.
Optimal dilutions to be determined by the researcher.
Immunogen
17aa peptide from mouse/human Calsarcins-2, conjugated to KLH. Epitope Location
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Calsarcin-2 antibody
Calcineurin is a Ca/calmodulin-dependent serine-threonine phosphatase that plays an important role in transducing Ca-dependent signals in a variety of cell types. Calcineurin has also been shown to have a profound influence on the properties of striated muscle cells, including cardiac muscle. A novel family of striated muscle-specific calcineurin-interacting proteins called calsarcins or Myozenins has been identified that interact and co-localizes with the Z-disc protein alpha-actinin. Two isoform of calsarcins, Calsarcin-1 and Calsarcin-2, with specific expression pattern have been identified in human, rat and mouse. Calsarcins tether calcineurin to the sarcomere of cardiac and skeletal muscle. Besides calcineurin and a-actinin, calsarcins interact with other Z-disc proteins g-filamin, telethonin and TCAP.
Product Categories/Family for anti-Calsarcin-2 antibody
References
• 1. Frey N (2000) PNAS 97, 14632-14637; Ahmad F (2000) Genomics 70, 347-353; Faulkner G (2000) JBC 275, 41234-41242; Takada F (2001) PNAS 98, 1595-1600;
Similar Products
Product Notes
The Calsarcin-2 (Catalog #AAA613701) is an Antibody produced from Host: Rabbit Source: Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti - Calsarcin-2 (Myozenin-1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Calsarcin-2 can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in ELISA and Western Blot. Other applications not tested. Dilution: Western Blot: 1:1000-1:5000 (ECL) ELISA: 1:10,000-1:50,000; Control peptide can be used to coat ELISA plates at 1ug/ml. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Calsarcin-2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calsarcin-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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