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PACAP Blocking Peptide | ADCYAP1 blocking peptide

PACAP Immunizing Peptide

Gene Names
ADCYAP1; PACAP
Reactivity
Human, Mouse, Rat, Dog, Cow, Pig
Synonyms
PACAP; PACAP Immunizing Peptide; ADCYAP1; adenylate cyclase activating polypeptide 1 (pituitary); MGC126852; OTTHUMP00000162201; adenylate cyclase activating polypeptide; ADCYAP1 blocking peptide
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat, Dog, Cow, Pig
Form/Format
100ug of dried peptide
Sequence
C-GKRYKQRVKNKGRR
Sequence Length
176
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
116
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18,835 Da
NCBI Official Full Name
pituitary adenylate cyclase-activating polypeptide preproprotein
NCBI Official Synonym Full Names
adenylate cyclase activating polypeptide 1
NCBI Official Symbol
ADCYAP1
NCBI Official Synonym Symbols
PACAP
NCBI Protein Information
pituitary adenylate cyclase-activating polypeptide
UniProt Protein Name
Pituitary adenylate cyclase-activating polypeptide
UniProt Gene Name
ADCYAP1
UniProt Synonym Gene Names
PACAP; PACAP-27; PACAP27; PACAP-38; PACAP38
UniProt Entry Name
PACA_HUMAN

NCBI Description

This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]

Uniprot Description

ADCYAP1: Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Belongs to the glucagon family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 18p11

Cellular Component: extracellular region

Molecular Function: neuropeptide hormone activity; peptide hormone receptor binding; pituitary adenylate cyclase activating polypeptide activity; protein binding; receptor binding

Biological Process: adenylate cyclase activation; cAMP-mediated signaling; cell-cell signaling; female pregnancy; neurite development; neuropeptide signaling pathway; positive regulation of GTPase activity; positive regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; regulation of G-protein coupled receptor protein signaling pathway; regulation of protein localization

Research Articles on ADCYAP1

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Product Notes

The ADCYAP1 adcyap1 (Catalog #AAA426079) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The PACAP Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Cow, Pig and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-GKRYKQRV KNKGRR. It is sometimes possible for the material contained within the vial of "PACAP, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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