Mouse anti-Human Thyroglobulin Monoclonal Antibody | anti-TG antibody
Anti-Thyroglobulin Antibody
Gene Names
TG; TGN; AITD3
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Protein A/G Affinity Purified
Synonyms
Thyroglobulin; Monoclonal Antibody; Anti-Thyroglobulin Antibody; anti-TG antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
AHC0247
Specificity
Human Thyroglobulin
Purity/Purification
Protein A/G Affinity Purified
Form/Format
Liquid
Concentration
100 ug/ 100 ul (varies by lot)
Sequence Length
2768
Applicable Applications for anti-TG antibody
Immunohistochemisty (IHC), Western Blot (WB)
Application Notes
IHC: 1:1000-1:3000
WB: 1:500-1:1000
WB: 1:500-1:1000
Immunogen
Recombinant Human Thyroglobulin
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Preparation and Storage
Stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use.
For extended storage, aliquot contents and freeze at -20 degree C or below.
Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
For extended storage, aliquot contents and freeze at -20 degree C or below.
Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Related Product Information for anti-TG antibody
Anti-Thyroglobulin Antibody is in ready-to-use format. Thyroglobulin serves as a precursor to thyroid hormones T4 and T3 and is can be found in thyroid follicular cells. Thyroglobulin expression is prevalent in thyroid follicular carcinomas for which this antibody is useful in recognizing. In addition, this Anti-Thyroglobulin antibody may be used in conjunction with Anti-Calcitonin to identify medullary thyroid carcinomas and primary and lung neoplasms if used with Anti-TTF1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
298,383 Da
NCBI Official Full Name
thyroglobulin
NCBI Official Synonym Full Names
thyroglobulin
NCBI Official Symbol
TG
NCBI Official Synonym Symbols
TGN; AITD3
NCBI Protein Information
thyroglobulin
UniProt Protein Name
Thyroglobulin
Protein Family
UniProt Gene Name
TG
UniProt Synonym Gene Names
Tg
NCBI Description
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
Uniprot Description
Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).
Research Articles on TG
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Product Notes
The TG tg (Catalog #AAA4156567) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Thyroglobulin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Thyroglobulin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemisty (IHC), Western Blot (WB). IHC: 1:1000-1:3000 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the TG tg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thyroglobulin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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