Rabbit anti-Human NGDN Polyclonal Antibody | anti-NGDN antibody
NGDN Antibody - middle region
NCBI and Uniprot Product Information
NCBI Description
Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008]
Uniprot Description
NGDN: Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs. Belongs to the SAS10 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; RNA-binding; Translation
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: small subunit processome; axon; cytoplasm; dendrite; nucleolus; chromosome, pericentric region; filopodium
Biological Process: regulation of translation; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)