Rubella IgM Antigen | IgM antigen
Rubella IgM MAX Antigen
Synonyms
Rubella IgM; Rubella IgM MAX Antigen; IgM antigen
Host
Vero Cells
Specificity
Antigen designed for Rubella IgM assays
Form/Format
Liquid; 0.1 M Sodium Carbonate, 0.1 M Sodium Chloride, pH 7.9 - 8.3
Viral Strain
HPV77
Source Note
Propagated in VERO Cells
Inactivation
Product inactivated by detergent and verified by Infectivity Testing (Plaque Assay)
Acceptable Range: 0 PFUlmL
Testing Results: 0 PFU/mL
Acceptable Range: 0 PFUlmL
Testing Results: 0 PFU/mL
Activity
ELISA Assay: Testing Results: Midpoint Titer (test antigen): 1724.15
Acceptable Range: -15% - +50% of Reference Antigen % of Reference: 18.89%
Testing Results: Midpoint Titer (reference antigen): 1450.21
Acceptable Range: -15% - +50% of Reference Antigen % of Reference: 18.89%
Testing Results: Midpoint Titer (reference antigen): 1450.21
Identity Assay
Western Blot
Acceptance: Only E I and E2 bands shown
Testing Results: Pass
Acceptance: Only E I and E2 bands shown
Testing Results: Pass
Preservative
None
Preparation and Storage
Store at <= -65 degree C. Avoid multiple freeze/thaw cycles.
Related Product Information for IgM antigen
Rubella viral infection (German Measles) is typically a mild and self-limiting disease that is most often contracted during childhood. Primary rubella infections are not common in adults, but if they occur, the infection may have serious consequences in pregnant women. Rubella Western Blot assays of IgM serum samples showed that false positive reactivity frequently is due to the reaction with Rubella capsid antigens. This may be due to cross-reactivity. Rubella IgMTM MAX Antigen was designed to be free of capsid proteins to address potential IgM cross-reactivity issues. Rubella IgM MAX Antigen is the envelope spike protein comprised of E 1 and E2 in the native configuration. These antigens give greater specificity in the detection of Rubella IgM antibodies. Specific Rubella IgM antibodies appear early after infection and react with the envelope proteins (spike protein) in the acute stage of the Rubella viral (German Measles) infections. Rubella IgMTM MAX Antigen is prepared by a patented process (patent #6,670,117 and #6,872,396 B2) of extraction of Rubella antigens from cells infected with Rubella Virus strain HPV77. Although the primary intent for this antigen is for the detection of IgM antibodies it can also be used for IgG if desired.
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Product Notes
The IgM (Catalog #AAA313597) is an Antigen produced from Vero Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Rubella IgM, Antigen" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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