MUM1 / PWWP Domain-Containing Protein MUM1 Recombinant Protein | MUM1 recombinant protein
Human MUM1 / PWWP Domain-Containing Protein MUM1 Recombinant Protein
Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
MUM1 / PWWP Domain-Containing Protein MUM1; Human MUM1 / PWWP Domain-Containing Protein MUM1 Recombinant Protein; PWWP domain-containing protein MUM1; Mutated melanoma-associated antigen 1; MUM-1; Protein expandere; EXPAND1; MUM1 recombinant protein
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Sequence Length
710
Applicable Applications for MUM1 recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Interacts with TP53BP1 (via BRCT domain); the interaction is not dependent on its phosphorylation status. Binds nucleosomes. Interacts with trimethylated 'Lys-36' of histone H3 (H3K36me3) (in vitro).
Entry Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
NCBI Official Full Name
PWWP domain-containing DNA repair factor 3A
UniProt Protein Name
PWWP domain-containing protein MUM1
Protein Family
UniProt Gene Name
MUM1
UniProt Synonym Gene Names
EXPAND1; MUM-1
Uniprot Description
MUM1: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. Belongs to the MUM1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell surface
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cytoplasm; nucleus
Molecular Function: nucleosome binding; protein binding
Biological Process: DNA repair; establishment and/or maintenance of chromatin architecture
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Product Notes
The MUM1 mum1 (Catalog #AAA2902220) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MUM1 / PWWP Domain-Containing Protein MUM1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the MUM1 mum1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MUM1 / PWWP Domain-Containing Protein MUM1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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