Vitamin D-Binding Protein/VDB/Gc-globulin Recombinant Protein | VDB recombinant protein
Recombinant Human Vitamin D-Binding Protein/VDB/Gc-globulin Protein (C-6His)
Gene Names
GC; DBP; VDB; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; DBP-maf; HEL-S-51
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Vitamin D-Binding Protein/VDB/Gc-globulin; Recombinant Human Vitamin D-Binding Protein/VDB/Gc-globulin Protein (C-6His); Vitamin D-Binding Protein; DBP; VDB; Gc-Globulin; Group-Specific Component; GC; VDB recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Sequence Positions
Leu17-Leu474
Sequence Length
474
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for VDB recombinant protein
Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 52.3 kDa
Actual Protein Molecular Mass: 53 kDa
Actual Protein Molecular Mass: 53 kDa
NCBI Official Full Name
vitamin D-binding protein isoform 1
NCBI Official Synonym Full Names
GC, vitamin D binding protein
NCBI Official Symbol
GC
NCBI Official Synonym Symbols
DBP; VDB; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; DBP-maf; HEL-S-51
NCBI Protein Information
vitamin D-binding protein
UniProt Protein Name
Vitamin D-binding protein
UniProt Gene Name
GC
UniProt Synonym Gene Names
Gc-MAF; GcMAF1 PublicationManual assertion based on opinion iniRef.15; Gc1 PublicationManual assertion based on opinion iniRef.15; DBP-maf
NCBI Description
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Uniprot Description
Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
Research Articles on VDB
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Product Notes
The VDB gc (Catalog #AAA2553376) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Leu17-Leu474. It is sometimes possible for the material contained within the vial of "Vitamin D-Binding Protein/VDB/Gc-globulin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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