Interleukin 20 Recombinant Protein | IL20Ra recombinant protein
Recombinant Interleukin 20 Receptor Alpha (IL20Ra)
Source: Prokaryotic expression
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- YSAYRYIQ VGKEKHPANL VLIYRNEIGK RVFNPTETLH SITLSTLDDS KISQTDMNLL DRSSDEVSVN NPEFSGSWEP NWEDAEGQHL GYSSHLVDIV CGVEQSDRDT SLTQHAWFNS PMPTGEADFE PQYKVLADFY KEGRDQQFCG SEEAARTEKL AEPQATLANL DPQLEDLQHL GQEHPGSEAR PEEEASTTLV DWDPRTGRLC IPSLPIFGHD LENYGCYERD HLSEDGLLSR LYENQAPDKSEEENENYLIQ FMEEWGLHVQ MES
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008]
Uniprot Description
IL20: Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3. Belongs to the IL-10 family.
Protein type: Secreted, signal peptide; Cytokine; Secreted
Chromosomal Location of Human Ortholog: 1q32
Cellular Component: extracellular space; extracellular region
Molecular Function: interleukin-20 receptor binding; interleukin-22 receptor binding; cytokine activity
Biological Process: positive regulation of osteoclast differentiation; regulation of inflammatory response; positive regulation of epidermal cell differentiation; positive regulation of JAK-STAT cascade; immune response; inflammatory response; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of keratinocyte differentiation
Research Articles on IL20Ra
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Product Notes
The IL20Ra il20 (Catalog #AAA2029935) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic expression and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Interleukin 20 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the IL20Ra il20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.MGSSHHHHH H SSGLVPRGSH MASMTGGQQM GRGSEF- YSAYRYIQ VGKEKHPANL VLIYRNEIGK RVFNPTETLH SITLSTLDDS KISQTDMNLL DRSSDEVSVN NPEFSGSWEP NWEDAEGQHL GYSSHLVDIV CGVEQSDRDT SLTQHAWFNS PMPTGEADFE PQYKVLADFY KEGRDQQFCG SEEAARTEKL AEPQATLANL DPQLEDLQHL GQEHPGSEAR PEEEASTTLV DWDPRTGRLC IPSLPIFGHD LENYGCYERD HLSEDGLLSR LYENQAPDKS EEENENYLIQ FMEEWGLHVQ MES. It is sometimes possible for the material contained within the vial of "Interleukin 20, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.