RAB34 cdna clone

RAB34

Cat. Num. AAA200618

• Gene Names: RAB34; RAH; NARR; RAB39
• Synonyms: RAB34; RAB39; RAH; RAB34 cdna clone

• Form/Format: Lyophilized
• Sequence: Nucleotide Sequence: ATGAACATTCTGGCACCCGTGCGGAGGGATCGCGTCCTGGCGGAGCTGCCCCAGTGCCTGAGGAAGGAGGCCGCTTTGCACGGGCACAAAGACTTCCACCCCCGCGTCACCTGCGCCTGCCAGGAGCACCGGACAGGCACCGTGGGATTTAAGATCTCCAAGGTCATTGTGGTGGGGGACCTGTCGGTGGGGAAGACTTGCCTCATTAATAGGTTCTGCAAAGACACCTTTGATAAGAATTACAAGGCCACCATTGGAGTGGACTTCGAGATGGAACGATTTGAGGTGCTGGGCATTCCCTTCAGTTTGCAGCTTTGGGATACCGCTGGGCAGGAGAGGTTCAAATGCATTGCATCAACCTACTATAGAGGAGCTCAAGCCATCATCATTGTCTTCAACCTGAATGATGTGGCATCTCTGGAACATACCAAGCAGTGGCTGGCCGATGCCCTGAAGGAGAATGACCCTTCCAGTGTGCTTCTCTTCCTTGTAGGTTCCAAGAAGGATCTGAGTACCCCTGCTCAGTATGCGCTGATGGAGAAAGACGCCCTCCAGGTGGCCCAGGAGATGAAGGCTGAGTACTGGGCAGTCTCATCTCTCACTGGTGAGAATGTCCGAGAATTCTTCTTCCGTGTGGCAGCACTGACCTTTGAGGCCAATGTGCTGGCTGAGCTGGAGAAATCGGGGGCTCGACGCATTGGGGATGTTGTCCGCATCAACAGTGATGACAGCAACCTCTACCTAACTGCCAGCAAGAAGAAGCCCACATGTTGCCCATGA; ; Translation Sequence: MNILAPVRRD RVLAELPQCL RKEAALHGHK DFHPRVTCAC QEHRTGTVGF KISKVIVVGD LSVGKTCLIN RFCKDTFDKN YKATIGVDFE MERFEVLGIP FSLQLWDTAG QERFKCIAST YYRGAQAIII VFNLNDVASL EHTKQWLADA LKENDPSSVL LFLVGSKKDL STPAQYALME KDALQVAQEM KAEYWAVSSL TGENVREFFF RVAALTFEAN VLAELEKSGA RRIGDVVRIN SDDSNLYLTA SKKKPTCCP
• Sequence Length: 259

• Species: Human
• Chromosome Location: 17q11.2
• OMIM Reference Number: 610917
• cDNA Size: 780bp
• Vector Description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
• Vector: (puc19-derived cloning vector)
• Preparation Before Usage: 1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
• Preparation and Storage: Store the plasmid at -20 degree C.

Related Product Information for RAB34 cdna clone

RAB34 encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. This gene overlaps and shares exon structure with the nine-amino acid residue-repeats (NARR) gene, which encodes a functionally distinct nucleolar protein from a different reading frame.

Product Categories/Family for RAB34 cdna clone

Signal Transduction; Transportation

NCBI and Uniprot Product Information

• NCBI GI #: 222144311
• NCBI GeneID: 83871
• NCBI Accession #: NP_114140.4
• NCBI GenBank Nucleotide #: NM_031934.5
• UniProt Accession #: Q9BZG1
• NCBI Official Full Name: ras-related protein Rab-34 isoform 1
• NCBI Official Synonym Full Names: RAB34, member RAS oncogene family
• NCBI Official Symbol: RAB34
• NCBI Official Synonym Symbols: RAH; NARR; RAB39
• NCBI Protein Information: ras-related protein Rab-34
• UniProt Protein Name: Ras-related protein Rab-34
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB34
• UniProt Synonym Gene Names: RAB39; RAH
• UniProt Entry Name: RAB34_HUMAN

NCBI Description

This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. An alternatively spliced transcript variant produces the nine-amino acid residue-repeats (NARR) protein, which is a functionally distinct nucleolar protein resulting from a different reading frame. [provided by RefSeq, Dec 2016]

Uniprot Description

RAB34: Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, monomeric; G protein, monomeric, Rab; Nucleolus

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: Golgi apparatus; Golgi cisterna; phagocytic vesicle membrane; Golgi stack; perinuclear region of cytoplasm; phagocytic vesicle; vesicle

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; Ral GTPase binding

Biological Process: antigen processing and presentation; lysosome localization; metabolic process; Golgi to plasma membrane protein transport; Rab protein signal transduction