NME3 recombinant protein

Recombinant Human NME3 protein

Cat. Num. AAA1562157

• Gene Names: NME3; NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2
• Purity: >90% as determined by SDS-PAGE
• Synonyms: NME3; Recombinant Human NME3 protein; Nucleoside diphosphate kinase 3; NDK 3; NDP kinase 3; DR-nm23; Nucleoside diphosphate kinase C; NDPKC; nm23-H3; NME3 recombinant protein

• Host: E Coli
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.

• Species: Homo sapiens (Human)
• Protein Construction: A DNA sequence encoding the human NME3 (Met1-Tyr168) was fused with His tag
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Preparation and Storage: Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.; In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Related Product Information for NME3 recombinant protein

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.

Product Categories/Family for NME3 recombinant protein

Protein

NCBI and Uniprot Product Information

• NCBI GI #: 21264477
• NCBI GeneID: 4832
• UniProt Accession #: Q13232; Q9BWH4
• Molecular Weight: 169
• NCBI Official Full Name: Nucleoside diphosphate kinase 3
• NCBI Official Synonym Full Names: NME/NM23 nucleoside diphosphate kinase 3
• NCBI Official Symbol: NME3
• NCBI Official Synonym Symbols: NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2
• NCBI Protein Information: nucleoside diphosphate kinase 3; NDK 3; NDP kinase 3; NDP kinase C; nucleoside diphosphate kinase C; non-metastatic cells 3, protein expressed in
• UniProt Protein Name: Nucleoside diphosphate kinase 3
• Protein Family: Nucleoside diphosphate kinase
• UniProt Gene Name: NME3
• UniProt Synonym Gene Names: NDK 3; NDP kinase 3; NDPKC
• UniProt Entry Name: NDK3_HUMAN

Uniprot Description

NME3: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis. Belongs to the NDK family.

Protein type: Kinase, other; Kinase, nucleoside diphosphate; Nucleotide Metabolism - pyrimidine; EC 2.7.4.6; Apoptosis; Motility/polarity/chemotaxis; Nucleotide Metabolism - purine; Other group; NDK family

Chromosomal Location of Human Ortholog: 16q13.3

Cellular Component: mitochondrion; cytosol

Molecular Function: metal ion binding; nucleoside diphosphate kinase activity; ATP binding

Biological Process: GTP biosynthetic process; regulation of apoptosis; CTP biosynthetic process; apoptosis; pyrimidine nucleotide metabolic process; UTP biosynthetic process; nucleoside triphosphate biosynthetic process; nucleoside diphosphate phosphorylation; purine nucleotide metabolic process