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Toll-interacting protein B (tollipb) Recombinant Protein | tollipb recombinant protein

Recombinant Oncorhynchus mykiss Toll-interacting protein B (tollipb)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Toll-interacting protein B (tollipb); Recombinant Oncorhynchus mykiss Toll-interacting protein B (tollipb); tollipb recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-275, Full length protein
Sequence
MSTTISTQRGQVYIGELPQDFLRITPPQQQQQVQLDAQAAQQLQYGESLGTVRRLSITVVQAKLAKNYGMTRMDPYCRVRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHVTIPEGLREGSVVDEWYSLSGRQGDDKEGMINLVMSYANMTAGMHMSPPVVLMPTVYQQGVGYIPIAGVPTVYNQGMVPMGMPAAPTVAPQEAPCSEEDLKALQDMFPNLDREVIRTVIEAQQGNKDAAINTLLQMTEEL
Sequence Length
275
Species
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
30,592 Da
NCBI Official Full Name
Toll-interacting protein B
UniProt Protein Name
Toll-interacting protein B
UniProt Gene Name
tollipb
UniProt Synonym Gene Names
tollip2

Uniprot Description

Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates ().

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Product Notes

The tollipb tollipb (Catalog #AAA1482397) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-275, Full length protein. The amino acid sequence is listed below: MSTTISTQRG QVYIGELPQD FLRITPPQQQ QQVQLDAQAA QQLQYGESLG TVRRLSITVV QAKLAKNYGM TRMDPYCRVR LGYAVYETPT AHNGAKNPRW NKVIQCTVPP GVDSFYLEIF DERAFSMDDR IAWTHVTIPE GLREGSVVDE WYSLSGRQGD DKEGMINLVM SYANMTAGMH MSPPVVLMPT VYQQGVGYIP IAGVPTVYNQ GMVPMGMPAA PTVAPQEAPC SEEDLKALQD MFPNLDREVI RTVIEAQQGN KDAAINTLLQ MTEEL. It is sometimes possible for the material contained within the vial of "Toll-interacting protein B (tollipb), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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