Protocadherin Fat 1 (FAT1) Recombinant Protein | FAT1 recombinant protein

Recombinant Human Protocadherin Fat 1 (FAT1) , partial

Cat. Num. AAA1477888

• Gene Names: FAT1; FAT; ME5; CDHF7; CDHR8; hFat1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Protocadherin Fat 1 (FAT1); Recombinant Human Protocadherin Fat 1 (FAT1); partial; FAT1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 4203-4588aa; Partial
• Sequence: RKMISRKKKHQAEPKDKHLGPATAFLQRPYFDSKLNKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESVHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDTKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNGYHWDTSDWMPSVPLPDIQEFPNYEVIDEQTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAADELPPLPPEFSNQFESIHPPRDMPAAGSLGSSSRNRQRFNLNQYLPNFYPLDMSEPQTKGTGENSTCREPHAPYPPGYQRHFEAPAVESMPMSVYASTASCSDVSACCEVESEVMMSDYESGDDGHFEEVTIPPLDSQQHTEV

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for FAT1 recombinant protein

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and
or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and
or alternative promoter usage exist, but they have not been fully described.

NCBI and Uniprot Product Information

• NCBI GI #: 66346693
• NCBI GeneID: 2195
• NCBI Accession #: NP_005236.2
• NCBI GenBank Nucleotide #: NM_005245.3
• UniProt Accession #: Q14517
• Molecular Weight: 506,273 Da
• NCBI Official Full Name: protocadherin Fat 1
• NCBI Official Synonym Full Names: FAT atypical cadherin 1
• NCBI Official Symbol: FAT1
• NCBI Official Synonym Symbols: FAT; ME5; CDHF7; CDHR8; hFat1
• NCBI Protein Information: protocadherin Fat 1
• UniProt Protein Name: Protocadherin Fat 1
• Protein Family: Protocadherin
• UniProt Gene Name: FAT1
• UniProt Synonym Gene Names: CDHF7; FAT

NCBI Description

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact.