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Kallikrein-15 Recombinant Protein | KLK15 recombinant protein

Recombinant Human Kallikrein-15

Gene Names
KLK15; ACO; HSRNASPH
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Kallikrein-15; Recombinant Human Kallikrein-15; KLK15 Human; Kallikrein-15 Human Recombinant; Kallikrein-related peptidase 15; ACO; HSRNASPH; ACO protease; KLK15; KLK15 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
The KLK15 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSLLEGDEC APHSQPWQVA LYERGRFNCG ASLISPHWVL SAAHCQSRFM RVRLGEHNLR KRDGPEQLRT TSRVIPHPRY EARSHRNDIM LLRLVQPARL NPQVRPAVLP TRCPHPGEAC VVSGWGLVSH NEPGTAGSPR SQVSLPDTLH CANISIISDT SCDKSYPGRL TNTMVCAGAE GRGAESCEGD SGGPLVCGGI LQGIVSWGDV PCDNTTKPGV YTKVCHYLEW IRETMKRN
Sequence Length
255
Physical Appearance
Sterile filtered colorless solution.
Preparation and Storage
Store at 4°C if entire vial will be used within 2-4 weeks.
Store frozen at -20°C for longer periods of time.
For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Related Product Information for KLK15 recombinant protein
KLK15 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 258 amino acids (22-256a.a) and having a molecular mass of 28.2kDa. KLK15 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for KLK15 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
kallikrein-15 isoform 5 preproprotein
NCBI Official Synonym Full Names
kallikrein-related peptidase 15
NCBI Official Symbol
KLK15
NCBI Official Synonym Symbols
ACO; HSRNASPH
NCBI Protein Information
kallikrein-15; ACO protease; kallikrein-like serine protease; prostinogen
UniProt Protein Name
Kallikrein-15
Protein Family
UniProt Gene Name
KLK15
UniProt Entry Name
KLK15_HUMAN

NCBI Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

KLK15: Protease whose physiological substrate is not yet known. Belongs to the peptidase S1 family. Kallikrein subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; EC 3.4.21.-; Secreted; Protease

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: extracellular region

Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: proteolysis

Research Articles on KLK15

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Product Notes

The KLK15 klk15 (Catalog #AAA146522) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSLLE GDEC APHSQPWQVA LYERGRFNCG ASLISPHWVL SAAHCQSRFM RVRLGEHNLR KRDGPEQLRT TSRVIPHPRY EARSHRNDIM LLRLVQPARL NPQVRPAVLP TRCPHPGEAC VVSGWGLVSH NEPGTAGSPR SQVSLPDTLH CANISIISDT SCDKSYPGRL TNTMVCAGAE GRGAESCEGD SGGPLVCGGI LQGIVSWGDV PCDNTTKPGV YTKVCHYLEW IRETMKRN. It is sometimes possible for the material contained within the vial of "Kallikrein-15, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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