SEC14-like protein 1 (SEC14L1) Recombinant Protein | SEC14L1 recombinant protein

Recombinant Human SEC14-like protein 1 (SEC14L1)

Cat. Num. AAA1298759

• Gene Names: SEC14L1; SEC14L; PRELID4A
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: SEC14-like protein 1 (SEC14L1); Recombinant Human SEC14-like protein 1 (SEC14L1); SEC14L1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-715, Full length protein
• Sequence: MVQKYQSPVRVYKYPFELIMAAYERRFPTCPLIPMFVGSDTVNEFKSEDGAIHVIERRCKLDVDAPRLLKKIAGVDYVYFVQKNSLNSRERTLHIEAYNETFSNRVIINEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPRWSPPSITTSSETSSSSSKKQAASMAVVIPEAALKEGLSGDALSSPSAPEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILETWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCEVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAASSLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR
• Sequence Length: 715

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for SEC14L1 recombinant protein

This protein belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system. Multiple alternatively spliced transcript variants have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 221316684
• NCBI GeneID: 6397
• NCBI Accession #: NP_001034662.2
• NCBI GenBank Nucleotide #: NM_001039573.2
• UniProt Accession #: Q92503; Q99780; A8K4E8; B4DDI5; D5G3K1
• Molecular Weight: 77,132 Da
• NCBI Official Full Name: SEC14-like protein 1 isoform b
• NCBI Official Synonym Full Names: SEC14 like lipid binding 1
• NCBI Official Symbol: SEC14L1
• NCBI Official Synonym Symbols: SEC14L; PRELID4A
• NCBI Protein Information: SEC14-like protein 1
• UniProt Protein Name: SEC14-like protein 1
• Protein Family: SEC14-like protein
• UniProt Gene Name: SEC14L1
• UniProt Synonym Gene Names: SEC14L

NCBI Description

The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system. Multiple alternatively spliced transcript variants have been found for this gene; some variants represent read-through transcripts that include exons from the upstream gene C17orf86. [provided by RefSeq, Feb 2011]

Uniprot Description

May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation (PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters (PubMed:17092608).