HRAS-like suppressor 2 (HRASLS2) Recombinant Protein | HRASLS2 recombinant protein

Recombinant Human HRAS-like suppressor 2 (HRASLS2), partial

Cat. Num. AAA1285331

• Gene Names: HRASLS2; PLA1/2-2
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: HRAS-like suppressor 2 (HRASLS2); Recombinant Human HRAS-like suppressor 2 (HRASLS2); partial; HRASLS2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-132
• Sequence: MALARPRPRL GDLIEISRFG YAHWAIYVGD GYVVHLAPAS EIAGAGAASV LSALTNKAIV KKELLSVVAG GDNYRVNNKH DDRYTPLPSN KIVKRAEELV GQELPYSLTS DNCEHFVNHL RYGVSRSDQV TG
• Sequence Length: 132

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 8923526
• NCBI GeneID: 54979
• NCBI Accession #: NP_060348.1
• NCBI GenBank Nucleotide #: NM_017878.1
• UniProt Accession #: Q9NWW9; B9A7L8
• Molecular Weight: 17,394 Da
• NCBI Official Full Name: HRAS-like suppressor 2
• NCBI Official Synonym Full Names: HRAS like suppressor 2
• NCBI Official Symbol: HRASLS2
• NCBI Official Synonym Symbols: PLA1/2-2
• NCBI Protein Information: HRAS-like suppressor 2
• UniProt Protein Name: HRAS-like suppressor 2
• Protein Family: HRAS-like suppressor
• UniProt Gene Name: HRASLS2

NCBI Description

The protein encoded by this gene has both phospholipase and acyltransferase activities and acts as a tumor suppressor. The encoded protein can hydrolyze dipalmitoylated phosphatidylcholine (PC) to palmitic acid and lyso-PC. In addition, this protein can catalyze the N-acylation of phosphatidylethanolamine and can catalyze the O-acylation of lyso-PC to form PC. [provided by RefSeq, Jul 2016]

Uniprot Description

Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Catalyzes N-acylation of PE using both sn-1 and sn-2 palmitoyl groups of PC as acyl donor. Also catalyzes O-acylation converting lyso-PC into PC.