ZDHHC17 cdna clone
ZDHHC17 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
HIP14: a palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, PSD-95, GAD2, SYT1 and Huntingtin. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May be involved in the NF-kappa-B signaling pathway. Can cause cellular transformation, and is up-regulated in a number of types of human tumors. Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate, and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney. Three alternatively spliced isoforms have been described.
Protein type: Transferase; Membrane protein, multi-pass; EC 2.3.1.225; Tumor suppressor; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q21.2
Cellular Component: cytoplasm; Golgi apparatus; Golgi membrane; intracellular membrane-bound organelle
Molecular Function: identical protein binding; magnesium ion transmembrane transporter activity; palmitoyltransferase activity; protein binding; protein-cysteine S-palmitoleyltransferase activity; signal transducer activity
Biological Process: lipoprotein transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein palmitoylation
Research Articles on ZDHHC17
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Product Notes
The ZDHHC17 zdhhc17 (Catalog #AAA1267476) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcagcggg aggagggatt taacaccaag atggcggacg gcccggatga gtacgatacc gaagcgggct gtgtgcccct tctccaccca gaggaaatca aaccccaaag ccattataac catggatatg gtgaacctct tggacggaaa actcatattg atgattacag cacatgggac atagtcaagg ctacacaata tggaatatat gaacgctgtc gagaattggt ggaagcaggt tatgatgtac ggcaaccgga caaagaaaat gttaccctcc tccattgggc tgccatcaat aacagaatag atttagtcaa atactatatt tcgaaaggtg ctattgtgga tcaacttgga ggggacctga attcaactcc attgcactgg gccacaagac aaggccatct atccatggtt gtgcaactaa tgaaatatgg tgcagatcct tcattaattg atggagaagg atgtagctgt attcatctgg ctgctcagtt cggacatacc tcaattgttg cttatctcat agcaaaagga caggatgtag atatgatgga tcagaatgga atgacgcctt taatgtgggc agcatataga acacatagtg tggatccaac tagattgctt ttaacattca atgtttcagt taaccttggt gacaagtatc acaaaaacac tgctctgcat tgggcagtgc tagcagggaa taccacagtc attagccttc ttctggaagc tggagctaat gttgatgccc agaatatcaa gggcgaatca gcgcttgatt tggcaaaaca gagaaaaaat gtgtggatga tcaaccactt acaagaggca aggcaagcaa aaggatatga caatccgtcc ttccttagaa agctgaaagc tgataaggaa tttcggcaga aagtaatgtt aggaactcct ttcctagtta tttggctggt tgggtttata gcagacctaa atattgattc ttggctcatt aaagggctaa tgtatggtgg tgtttgggct acagtacagt ttctttcaaa atcctttttc gatcattcaa tgcatagtgc attgcccctt gggatatatt tggcaaccaa attctggatg tatgtgacgt ggttcttctg gttttggaat gatctcaact ttttatttat ccatcttcca ttccttgcca atagtgttgc acttttctac aattttggaa aatcttggaa atcagatcca gggattatta aagcaacaga agagcaaaag aaaaagacaa tagttgaact tgcagagaca ggaagtctgg acctcagtat attctgcagt acctgtttga tacgaaaacc ggtgaggtcc aaacattgtg gtgtgtgcaa ccgctgtata gcaaaatttg atcatcattg cccatgggtg ggtaactgtg taggtgcagg caaccataga tattttatgg gctacctatt cttcttgctt tttatgatct gctggatgat ttatggttgt atatcttact ggggactcca ctgtgagacc acttacacca aggatggatt ttggacatac attactcaga ttgccacgtg ttcaccttgg atgttttgga tgttcctgaa cagtgttttc cacttcatgt gggtggctgt attactcatg tgtcagatgt accagatatc atgtttaggt attactacaa atgaaagaat gaatgccagg agatacaagc actttaaagt cacaacaacg tctattgaaa gcccattcaa ccatggatgt gtaagaaata ttatagactt ctttgaattt cgatgctgtg gcctctttcg tcctgttatc gtggactgga ccaggcagta tacaatagaa tatgaccaaa tatcaggatc tgggtaccag ctggtgtag. It is sometimes possible for the material contained within the vial of "ZDHHC17, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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