Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) Recombinant Protein | ENTPD5 recombinant protein
Recombinant Bovine Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5)
NCBI and Uniprot Product Information
Uniprot Description
Function: Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling
By similarity.
Catalytic activity: GDP + H2O = GMP + phosphate.A nucleoside diphosphate + H2O = a nucleotide + phosphate.
Cofactor: Calcium
By similarity.Magnesium
By similarity.
Pathway: Protein modification; protein glycosylation.
Subcellular location: Endoplasmic reticulum membrane
By similarity; Single-pass type II membrane protein
By similarity.
Post-translational modification: N-glycosylated; high-mannose type
By similarity.
Sequence similarities: Belongs to the GDA1/CD39 NTPase family.
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Product Notes
The Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) entpd5 (Catalog #AAA1058570) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-432. The amino acid sequence is listed below: STVFHREQQT WFEGVFLSSM CPVNVSAGTL YGIMFDAGST GTRIHVYTFV QKVPDNTGQL PVLEGEIFDS VKPGLSAFVD QPKQGAETVQ ELLEVAKDSI PPSHWKRTPV VLKATAGLRL LPEEKAEALL FEVKEIFKKS PFLVPDDSVS IMDGSYEGIL AWVTVNFLTG QLHGHNQETV GTLDLGGAST QITFLPQFEK TLEQTPRDYL TSFEMFNSTY KLYTHSYLGF GLKAARLATL GALETAGIDG YTFRSACLPR WLEAEWIFGG VKYQYGGNQE AGEVGFEPCY AEVLRVVQGK LHQPDEVQRG SFYAFSYYYD RAVDTDMIDY EKGGVLKVED FERKAREVCD NLENFTSGSP FLCMDLSYIT ALLKDGFGFA SSTVLQLTKK VNNIETGWAL GATFHLLQSL GISH. It is sometimes possible for the material contained within the vial of "Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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